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1.
Adv Gerontol ; 32(3): 439-444, 2019.
Article Ru | MEDLINE | ID: mdl-31512432

The article presents the results of a study of the effectiveness of the addition of a standard course of conservative therapy to 104 patients of the older age group with coxarthrosis deforming the drug «Cytoflavin¼ and cognitive-behavioral therapy courses. It was found that such scheme increases the effectiveness of therapeutic interventions, which manifests itself as the improvement of the mental and physical components of quality of life by reducing pain and increasing the functionality of some of the affected hip. At the heart of positive clinical effect is a decrease in processes of inflammation and reduction of tension of regulatory processes in the organism.


Cognitive Behavioral Therapy , Flavin Mononucleotide , Inosine Diphosphate , Niacinamide , Osteoarthritis, Hip , Succinates , Aged , Drug Combinations , Flavin Mononucleotide/pharmacology , Flavin Mononucleotide/therapeutic use , Humans , Inosine Diphosphate/pharmacology , Inosine Diphosphate/therapeutic use , Neuroprotective Agents/pharmacology , Neuroprotective Agents/therapeutic use , Niacinamide/pharmacology , Niacinamide/therapeutic use , Osteoarthritis, Hip/drug therapy , Osteoarthritis, Hip/therapy , Quality of Life , Succinates/pharmacology , Succinates/therapeutic use
2.
Stomatologiia (Mosk) ; 95(2): 14-17, 2016.
Article Ru | MEDLINE | ID: mdl-27239991

The aim of the study was to evaluate the effect of combined use of Cytoflavin and cognitive therapy on the dynamics of psychosomatic status and effectiveness of the treatment of generalized periodontitis in elderly patients. The results of treatment of 103 patients aged 60 and older were analyzed. All patients received standard therapy for 10-14 days depending on the severity of the process. In addition, the patients of the main group (51 patients) received Cytoflavin: 2 tabs. 2 times a day with an interval between doses of 8-10 hours for 25 days, and cognitive therapy aimed at training alternative realistic way of life perception. Treatment results were monitored by PMA, Russell periodontal index (PI), Green-Vermillion hygienic index. Psychosomatic dynamics was assessed by means of Spielberger anxiety scale and SUN" methods of before and after a month of treatment. The inclusion in the treatment regimen of Cytoflavin and cognitive therapy had a positive impact: reduction of PMA by 61.8%, PI by 45.3% and Green-Vermillion index by 39.8%. The psychosomatic tests proved anxiety level decrease by 28.7% in terms of "reactive" anxiety and 31.5% in terms of "personal" anxiety, emotional status (21.2%), activity (21.7%) and mood (21.8%) improvement.


Antioxidants/therapeutic use , Cognitive Behavioral Therapy , Flavin Mononucleotide/therapeutic use , Inosine Diphosphate/therapeutic use , Niacinamide/therapeutic use , Periodontitis/therapy , Succinates/therapeutic use , Aged , Aged, 80 and over , Combined Modality Therapy , Drug Combinations , Humans , Middle Aged , Periodontitis/drug therapy , Periodontitis/psychology , Treatment Outcome
3.
Adv Gerontol ; 29(5): 816-821, 2016.
Article Ru | MEDLINE | ID: mdl-28556655

The authors studied the efficiency of the expansion of the standard course of conservative therapy of deforming coxarthrosis by appointment Cytoflavin and behavioral therapy. The study was performed on 104 elderly patients. It was found that the addition of the existing scheme increases the effectiveness of therapeutic interventions, which manifests itself as the improvement of the mental and physical components of quality of life by reducing pain and increasing the functionality of some of the affected hip. At the heart of positive clinical effect is a decrease in processes of inflammation and reduction of tension of regulatory processes in the organism. Positive quality extra medical appointments was the absence of significant side effects when taken orally Cytoflavin requiring discontinuation of the drug, as well as the absence of failure patients from further sessions of behavioral therapy.


Cognitive Behavioral Therapy/methods , Flavin Mononucleotide/administration & dosage , Inosine Diphosphate/administration & dosage , Niacinamide/administration & dosage , Osteoarthritis, Hip , Pain , Quality of Life , Succinates/administration & dosage , Aged , Combined Modality Therapy/methods , Drug Combinations , Female , Humans , Male , Neuroprotective Agents/administration & dosage , Osteoarthritis, Hip/complications , Osteoarthritis, Hip/diagnosis , Osteoarthritis, Hip/psychology , Osteoarthritis, Hip/therapy , Pain/diagnosis , Pain/etiology , Pain/psychology , Pain Management/methods , Treatment Outcome
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